Special Issue "Pathogenesis of Emerging Zoonotic Viral Infections"
A special issue of Pathogens (ISSN 2076-0817).
Deadline for manuscript submissions: 31 May 2021.
Interests: host innate immune evasion by emerging pathogens; particularly arenaviruses, host-virus interactions, restriction factors, antivirals, structure-function relationships of viral proteins
Interests: cytotoxic T lymphocytes (CTL); Multiple Sclerosis; central nervous system (CNS); Epstein Barr Virus (EBV); HERV
Special Issues and Collections in MDPI journals
The increasing emergence of zoonoses has devastating impacts on global public health and socio-economic development. Approximately 60% of all human infectious diseases are caused by zoonotic transmission from domestic animals, birds and wildlife; and an alarming 75% of recently emerged human infectious diseases are zoonotic in origin.Viral pathogens are a major threat worldwide; being responsible for significant disease emergence including highly pathogenetic avian influenza, Zika virus disease and viral haemorrhagic fevers caused by arenaviruses and Ebola viruses. The spread of these viral outbreaks can vary from confined clusters of cases to millions of cases globally, with hundreds of thousands or more, of associated deaths. Indeed, the current COVID-19 disease pandemic caused by a novel severe acute respiratory syndrome coronavirus, SARS-CoV-2, of animal origin, has led to significant morbidity and mortality rates, with substantial impact on public health resources and disruptions to global economic activity. The SARS-CoV-2 pandemic has highlighted the global challenges surrounding the detection and control strategies against zoonotic pathogens. Understanding the nature of viral zoonotic disease pathogenesis and unravelling the complex mechanisms involved in establishing infection and disease is crucial for identifying risk factors that influence transmission from reservoir hosts, and in providing key information that can improve diagnosis, treatment strategies and prevention. Further, studying the genetic diversity of emerging viruses and the molecular details of key differences in host innate and adaptive immune responses to infection, can expand our understanding of the host-virus co-evolution of hosts and impact on the development of antiviral vaccine and novel therapies. This Special Issue invites original research papers, reviews, and short communications about the pathogenesis of emerging and re-emerging zoonoses. Potential scope includes, but is not limited to: · Emerging and re-emerging virus infections· Genetic diversity and zoonotic potential· Virus-host interactions· Pathogenesis- entry, replication, spread· Molecular aspects of host immune responses· Diagnosis and disease management, i.e. prevention and control· SARS and SARS-CoV-2· Vaccines and therapeutics.
Dr. Toshana Foster
Dr. Svetlana Khaiboullina
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, . Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- emerging viruses
- genetic diversity
- host immunity
- host restriction factors
- therapeutic strategies